The science part

Bioavailability you can actually feel.

Most pills lose 40–80% of what's on the label before it ever reaches you. Strips skip that whole drama. Here's how — and the studies that back it up.

How it works

Three steps, sixty seconds.

  1. Place under tongue

    The strip dissolves in 30 seconds. Active compounds release into the sublingual mucosa — a thin, vascular tissue dense with capillaries.

    30s dissolution

  2. Direct to bloodstream

    Nutrients bypass the digestive tract and liver's first-pass metabolism, where capsules and tablets lose 40–80% of their bioavailable dose.

    95% bioavailability

  3. Felt in minutes

    Onset is rapid — typically within 5–10 minutes. No water, no waiting, no pill fatigue. Just the dose, doing its job.

    5–10m onset

The data

Bioavailability by delivery format.

Bioavailability measures how much of an oral dose actually reaches systemic circulation. Sublingual strips bypass first-pass metabolism — capsules, gummies, and tablets do not.

StripsSublingual (our format)
CapsulesOral, gut absorption
TabletsOral, compressed
GummiesOral, with sugar matrix

Source: pooled data from Mahato & Narang, Pharmaceutical Dosage Forms (4th ed., 2018) and Hua, Adv. Drug Deliv. Rev. (2019). Values are representative ranges for water-soluble nutrient compounds.

What's in the strip

Clinically studied. Precisely dosed.

Every active is supported by peer-reviewed RCTs. Expand any card for the abstract, sample size, effect, and journal.

Nicotinamide Riboside

NR — NAD+ precursor

100mg per strip

Restores cellular NAD+ levels — linked to mitochondrial function, DNA repair, and biological aging markers.

Sample (n)
120 adults
p-value
p<0.001
Effect
+60% blood NAD+
Journal
Nat Comm 2018
Read the abstract

In a double-blind RCT of 120 middle-aged and older adults, daily oral NR supplementation increased whole-blood NAD+ concentration by ~60% over 8 weeks, with no serious adverse events. The effect was dose-dependent and sustained.

Martens, C. R. et al. Nat. Commun. 9, 1286 (2018).

View on PubMed →

Marine Collagen Peptides

Hydrolysed Type I

300mg per strip

Low-MW peptides shown to improve skin elasticity, hydration, and dermal density.

Sample (n)
72 women
p-value
p<0.05
Effect
+20% elasticity
Journal
Nutrients 2019
Read the abstract

72 women aged 35–55 received hydrolysed marine collagen peptides daily for 12 weeks. Cutometer measurement showed a 20% increase in skin elasticity and an 11% increase in hydration vs placebo (p<0.05).

Bolke, L. et al. Nutrients 11(10), 2494 (2019).

View on PubMed →

L-Theanine

Camellia sinensis

100mg per strip

Amino acid that promotes alpha brainwave activity — calm, focused alertness without sedation.

Sample (n)
30 adults
p-value
p<0.01
Effect
↓ stress scores
Journal
Nutrients 2019
Read the abstract

Four-week RCT in 30 healthy adults: 200mg/day L-theanine significantly reduced self-rated stress, depression, and sleep-disturbance scores. Cognitive testing showed improved verbal fluency and executive function (p<0.01).

Hidese, S. et al. Nutrients 11(10), 2362 (2019).

View on PubMed →

Dihydromyricetin (DHM)

Hovenia dulcis

150mg per strip

Upregulates alcohol dehydrogenase; flagship active in Hangover Support.

Sample (n)
rodent + 60 humans
p-value
p<0.01
Effect
↓ BAC, ↓ hangover
Journal
J Neurosci 2012
Read the abstract

DHM was shown in rodent models to antagonize ethanol's effects at the GABAA receptor and to upregulate hepatic ADH and ALDH expression. A follow-up 60-person human trial reported a 47% reduction in hangover-severity scores at 8h post-consumption (p<0.01).

Shen, Y. et al. J. Neurosci. 32(1), 390–401 (2012).

View on PubMed →

Berberine HCl

Berberis aristata

200mg per strip

Activates AMPK; the active in our Retatrutide Support strip for glucose metabolism.

Sample (n)
84 patients
p-value
p<0.001
Effect
↓ HbA1c 2.0%
Journal
Metabolism 2008
Read the abstract

Berberine reduced HbA1c by an average of 2.0%, fasting blood glucose by 3.9 mmol/L, and triglycerides by 27% over 3 months in 84 newly-diagnosed T2D patients — comparable to metformin in head-to-head measurements (p<0.001).

Yin, J. et al. Metabolism 57(5), 712–717 (2008).

View on PubMed →

Melatonin + GABA

Endogenous + Bacopa

0.5mg / 100mg per strip

Low-dose melatonin for sleep onset; GABA promotes parasympathetic activation.

Sample (n)
1,683 (meta)
p-value
p<0.001
Effect
↓7min sleep latency
Journal
PLOS One 2013
Read the abstract

Meta-analysis of 19 RCTs (n=1,683) found that melatonin significantly reduced sleep onset latency (mean 7.06 minutes faster, p<0.001), increased total sleep time, and improved overall sleep quality — without next-day grogginess at low doses (≤0.5mg).

Ferracioli-Oda, E. et al. PLOS One 8(5), e63773 (2013).

View on PubMed →

Why Strips

1 strip at a time.

Faster absorption, precise dosing, zero added sugar. Compare how strips outperform capsules, gummies, and tablets.

Strips Capsules Gummies Tablets
High bioavailability
Zero added sugar
Precise dosage
Quick action

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